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KMID : 1101420200520020119
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Korean Journal of Clinical Laboratory Science
2020 Volume.52 No. 2 p.119 ~ p.127
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Association between Pulse Pressure and Impaired Pulmonary Function in Non-Smoking Adults
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Yoon Hyun
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Abstract
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According to previous studies, an impaired pulmonary function is associated with arterial stiffness (AS). The pulse pressure (PP) is an important predictor of AS, but the association of an impaired pulmonary function with the PP is unclear. Therefore, this study assessed the associations between the PP and the predicted forced vital capacity (predicted FVC) and predicted forced expiratory volume in one second (predicted FEV1) in Korean non-smoking adults. The data obtained from 6,857 adults during the 2013∼2015 Korean National Health and Nutrition Examination Survey were analyzed. After adjusting for the related variables, the ORs of restrictive pulmonary disease (RPD, the predicted FVC＜80.0% with FEV1/FVC≥70.0%) using the normal PP group (PP≤60 mmHg) as a reference group was significant for the high PP group (PP＞60 mmHg; 1.337 [95% confidence interval (CI), 1.049∼1.703]). In addition, the ORs of obstructive pulmonary disease (OPD, FEV1/FVC＜70.0%) using the normal PP group as a reference group were significant for the high PP group (1.339 [95% CI, 1.093∼1.642]). In conclusion, a high PP is positively associated with both RPD and OPD in Korean non-smoking adults.
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KEYWORD
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on-smoker, Obstructive pulmonary diseases, Pulse pressure, Restrictive pulmonary diseases
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